bis-AB-oh-lol
The chamomile terpene. Skin-healing, anti-irritant, and deeply calming. The most skin-friendly cannabis terpene.
Alpha-bisabolol is the primary active compound in chamomile and is widely used in cosmetics for its skin-healing, anti-irritant properties. In cannabis, it contributes calming, anti-inflammatory effects and is particularly valuable in topical formulations.
Alpha-bisabolol is a sesquiterpene alcohol found most abundantly in German chamomile (Matricaria chamomilla) and the candeia tree (Eremanthus erythropappus). It is one of the most widely used cosmetic ingredients in the world, valued for its skin-soothing, anti-irritant, and wound-healing properties.
In cannabis, bisabolol is found in relatively low concentrations but contributes meaningfully to the overall effect profile. It is associated with calming, anti-anxiety effects and is particularly valuable in cannabis topicals where its skin-healing properties complement cannabinoids' anti-inflammatory effects.
Research has demonstrated bisabolol's anti-inflammatory, antimicrobial, and wound-healing properties. It enhances skin penetration of other compounds — making it a valuable ingredient in topical cannabis formulations where it can increase cannabinoid absorption.
Bisabolol has also shown anti-tumor properties in preclinical research, inducing apoptosis in leukemia cells and enhancing the efficacy of chemotherapy drugs. Its calming, anti-anxiety effects in cannabis are well-reported by users, though clinical data is limited.
To maximize Bisabolol in your vapor, set your vaporizer to just above its boiling point:
Lower temperatures preserve more terpenes; higher temperatures extract more cannabinoids.
Full-spectrum products preserve Bisabolol and all other terpenes alongside cannabinoids for the complete entourage effect. Our editorial team's top picks:
World-leading scientist formulation. Standardized full spectrum profiles, not just a CBD count. Pioneered the cannabis topical liniment spray.
Liniment spray is the most effective topical staff have tested.
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Same world-leading scientist as CBDWellness. Verified THC non-detect on every batch by ISO 17025 accredited lab — trusted by military, athletes, and law enforcement.
The only broad spectrum brand staff trust for drug-tested professionals.
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Same world-leading scientist as CBDWellness. Standardized THC formulations for consistent, reliable therapeutic effects. Available at licensed dispensaries.
THC topical liniment spray is the most effective cannabis topical staff have tested.
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Editorial Disclosure: These brands are selected by our editorial team based on independent staff testing, lab result analysis, and 7 years of annual awards data. We do not accept payment for editorial placement. See our Annual Awards methodology for full details.