neh-ROL-ih-dol
Woody, floral, deeply sedating. The most potent sleep-inducing terpene — found in neroli and jasmine.
Nerolidol is a sesquiterpene alcohol found in neroli, jasmine, and ginger. It is the most potently sedating cannabis terpene, with demonstrated anti-parasitic properties and significant skin penetration enhancement for topical formulations.
Nerolidol (trans-nerolidol) is a sesquiterpene alcohol found in neroli (bitter orange blossom), jasmine, ginger, and cannabis. It produces a complex woody, floral, slightly fruity aroma and is one of the most potently sedating terpenes in cannabis.
Research has demonstrated nerolidol's remarkable anti-parasitic properties — it has shown efficacy against malaria, leishmaniasis, and Chagas disease in preclinical studies. This makes it one of the most pharmacologically interesting cannabis terpenes from a global health perspective.
Nerolidol is also a potent skin penetration enhancer, increasing the absorption of drugs and cannabinoids through the skin by up to 20-fold in some studies. This makes it extremely valuable in topical cannabis formulations.
In cannabis, nerolidol is associated with deeply sedating, relaxing effects. It is found in strains like Skywalker OG and Jack Herer, where it contributes to the overall effect profile alongside other terpenes.
To maximize Nerolidol in your vapor, set your vaporizer to just above its boiling point:
Lower temperatures preserve more terpenes; higher temperatures extract more cannabinoids.
Full-spectrum products preserve Nerolidol and all other terpenes alongside cannabinoids for the complete entourage effect. Our editorial team's top picks:
World-leading scientist formulation. Standardized full spectrum profiles, not just a CBD count. Pioneered the cannabis topical liniment spray.
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Same world-leading scientist as CBDWellness. Standardized THC formulations for consistent, reliable therapeutic effects. Available at licensed dispensaries.
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Editorial Disclosure: These brands are selected by our editorial team based on independent staff testing, lab result analysis, and 7 years of annual awards data. We do not accept payment for editorial placement. See our Annual Awards methodology for full details.